Is painless PENTAXIM vaccine banned???

Hey all..

Had another hectic weekend… One of the important things I did this weekend was to get my baby vaccinated that was due for 14 weeks of age.

This is his 3rd dose for DTaP, HiB & Polio (more on these below).

The baby was given PENTAXIM vaccine for the previous doses at 6 weeks & 10 weeks of age. This time the paed informed us that the particular vaccine has been banned by the Indian Government!

Let’s see about this vaccine in detail, why is it banned all of a sudden & what is the replacement for this.

pentaxim

WHAT IS PENTAXIM

Pentaxim as the name goes is a combination vaccine against 5 different types of infections –

1. DIPTHERIA

2. TETANUS

3. PERTUSSIS

4. POLIOMYELITIS (or simply Polio)

5. HiB – Haemophilus Influenzae Type B (capable of causing – Meningitis (Brain Fever), Septicaemia (Bacteria in the bloodstream), Cellulitis (Skin infection), Arthritis, Epiglottitis, Pneumopathy (Any lung disease) & Osteomyelitis (Infection of the bone)).

The limelight of Pentaxim is its ability to deliver feverless, painless acellular doses against Pertussis infection. It of course comes at a price!

Sounds to be a boon of vaccine ain’t it! It was initially launched in 1997.

WHEN TO ADMINISTER?

Vaccinations for all the 5 diseases mentioned above need to be administered to the baby in the following stages –

1st dose – 6 weeks of age

2nd dose – 10 weeks of age

3rd dose – 14 weeks of age

1st booster – 18 months

2nd booster – 5 years

WHY THE BAN?

There have been numerous studies over the years, that the dosage of vaccine in Pentaxim against Pertussis is low, that it is not able to protect humans from infection in the long run.

A recent study by WHO also states that pertussis (respiratory disease, which spreads through contact) is on the rise again & is prevalent among 5+ years old children in the United States & Europe, where this vaccine has been adopted as part of the national immunization schedule.

This vaccine has already been banned in developed countries, on WHO’s recommendation.

Pentaxim is easily available across the world and is part of India’s national immunization schedule as well, due to its capability of acting against 5 diseases in one go!

Initially, I did read reports in the paper, that there is a shortage of Pentaxim vaccines in the country early in January 2014. But now it has come out to light that the government has officially banned the vaccine, though very late when compared to US & Europe.

baby-getting-vaccinated

REPLACEMENT FOR PENTAXIM?

Yes… There is easy replacement available.

QUADRAVAC vaccine is administered to fight against the four diseases listed above except polio. You have to administer POLIOVAC (Inactivated Polio Vaccine, in the form of injection) for vaccination against polio separately.

So, it makes it 2 injections instead of 1 Pentaxim injection!

The catch here is QUADRAVAC does not deliver painless, acellular Pertussis component! 😦

It is quite painful even while injecting to the baby, plus there are high chances of swelling around the area of injection for upto 10 hrs. post vaccination.

The baby will get fever & feel pain in the area of injection along with swelling.. which is not good news for any mom…

But seeing the brighter side of life… infection prevention weighs higher than pain prevention.

I am glad that my baby’s paed explained all this to me clearly (amidst the big queue of people waiting for their baby’s vaccination), so that I can feel comforted about the pain & swelling that is inevitable after the vaccination process.

So, if your baby is due for its vaccine, do opt for a different combo of vaccine other than PENTAXIM, to avoid chances of infection in later stages of life! 🙂

MY CASE 

My baby cried like hell when the injection was administered. Heavy tears rolled down his eyes. Something new for us from our earlier vaccination experiences!

So, the alternative injection does deliver medicine with huge pain! Be prepared…

As the doc mentioned, his thighs (where vaccine was administered) swell a little after about 2 hrs. and the baby couldn’t handle the pain at all.. wasn’t able to kick or move his legs freely like before.. and kept crying all day.

I had to give him 2 shots of paracetamol drops to bring down the fever & pain, and the  baby was back bouncing after about 10-12 hrs. of vaccination! 😀

Did you find this post useful? What kind of posts would you like to see in this space? Do drop in your comments…

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56 comments

  1. Azad….i read ur comments on doctors… Shame on u..
    For all those who call doctors cheats, robber, for charging them bare minimum. (Yes I mean it, it’s BARE MINIMUM….) Here are the facts.

    Average stitching cost by a tailor- 400 & above
    Plumber & electrician cost- 500 & above.
    ( Education— ????? )

    “”Figures compiled by The Lancet show that the cost of a caesarean section is estimated at
    $15,500 in the US, which was only $5,000 costlier than in Australia.

    A normal birth in Australia cost $6,775, while in America it was $10,232.”” Convert in INR.

    People come to us, with expectations of world class treatment, but they don’t want to spend on their own health. They cut around corners & land up in trouble. ( For which they hold doctors responsible. Hypocrites!!!! )

    They self medicate, decide fr themselves which investigations they ll get done, take ayurvedic, allopathic, homeopathic, some baba therapy & wat not. But ll nt take any treatment properly. These days with Google they think they know better than sm1 who has studied medicine fr 10 years. SERIOUSLY?????

    IF YOU CAN’T SPEND ON YOUR OWN HEALTH, YOU ARE LIVING A FOOL’s LIFE.

    Its high time YOU SHOULD TAKE RESPONSIBILITY of your casual attitude towards YOUR OWN HEALTH !!!!!!!!

    Like

  2. in more states all moms intrusted pentaxim vaccin (for pain less) and what is altered vaccin to pentaxim vaccination .and if already 6weeks vaccination is taken then what is remedy kindly guide us for next vaccination(10 weeks)for our baby

    Like

  3. It is not banned by WHO or Indian Government
    (Please don’t fall for such rumors, do some research guys.
    I was shocked to see the comments by clueless parents putting their children through torture. Please read both the links i have shared.)

    http://www.who.int/bulletin/volumes/86/6/07-042143/en/

    “In summary, this study demonstrated that the DTaP–IPV//PRP~T combination vaccine was highly immunogenic for all antigens, well tolerated and safe when given to infants at 6, 10 and 14 weeks of age, a schedule used frequently in the WHO EPI. Moreover, it could be given concomitantly with monovalent hepatitis B vaccine at either 0, 6 and 14 weeks of age or 6, 10 and 14 weeks of age. However, the magnitude of the hepatitis B immune response was greater when the first dose was given at birth. The immunogenicity and safety of the DTaP–IPV//PRP~T combination vaccine in healthy children in the Philippines were similar to those observed in a European historical control study that administered the same vaccine at 2, 3 and 4 months of age.”

    There is also a research paper by Lady Hardinge Medical College and Associated Hospitals stating that the efficacy of Pentaxim is good.

    http://indianpediatrics.net/oct2012/oct-793-798.htm

    Conclusion: The DTaP-IPV//PRP-T vaccine booster at 18-19 months of age was well tolerated and induced strong antibody responses.

    Dear CrappyMom,
    I would suggest that you please delete this post as it is misleading parents and their children are suffering, i would recommend writing a post that it is not banned and stating the facts from the research papers that I have shared, this will help the parents who are regular on your blog and have doubts about the vaccine because of the above post.

    Also, if this is your husband, (copy-paste post) ask him to delete it as well.
    http://himanshoo.in/painless-vaccine-is-banned/

    P.S. If your doctor really said that the vaccine is banned, please find a new pediatrician, and share his name, as parents should stop taking their children to his clinic.

    Like

    1. Dear Kunal,

      Nobody is concluding on something here or suggesting/advocating something via this post.

      This is a blog where I am sharing my personal parenting experience. My doc told Pentaxim is banned and so did many other paeds! We are all just discussing this over here.

      What this post deals with is what are all in Pentaxim, what my doc told me and what I could find about it on Internet, alternative for Pentaxim, etc.

      It is for the parents-paed to collaboratively affirm and decide what is good for whom! I am not judging anything here.

      Also, regarding the post reference you gave on another blog – No! that is not my husband and thanks for letting know about plagiarism over there.

      Thanks for stopping by to comment.

      Like

    2. Dear Kunal,
      After seeing your post am bit cool down,.

      I was keeping my hand on forehear n searching the web for pentaxim stories.
      I was worried as my little son Gautham, already taken 4 shots of pentaxim now 5th one in que but vaccine is not available in market.
      Can i give QUADRAVAC for now ?
      If you have any details kindly share

      Like

  4. PENTAXIM- A BIG YES to administrate it.

    Firstly, I would pay my regards to every parent out here.
    I would like to Start with that PENTAXIM is not a banned Vaccine neither in India and nor in any of the Europian country.It is a safe and efficacious vaccine. Infact, it is the only PERTUSSIS vaccine in India which has been studied and has efficacy data.

    I don’t say wP vaccines are bad/Inefficatious/Less Efficacious infact they are for masses so that the parents who cannot afford the comfort and Efficacy at the same time wP is best as we firstly need to increase the coverage to 100 percent which is merely 70% in India.

    If we talk about the efficacy of wP vaccine I would like to inform you that wP vaccine efficacy varies from 42% to 92% and this is according to the foreign Data (U.K) and as far as India is concerned not even a single efficacy trial has been estd.

    For Pentaxim, trials on Indian babies have been done and has well established efficacy.

    But YES, whether you go for aP or wP never forget to go for Booster dose after 5 years.

    I am a Senior Pead. I am doing my Private Practice Since 20 Years and I am administrating Pentaxim since 2008 and touchwood i have not seen even a single case of pertussis to those babies to whom I have administered Pentaxim followed by the comfort and compliance to Parents and Babies.

    One can go for both, aP and wP, but the bottom line is EVERYONE MUST GO FOR VACCINATION.

    REGARDS…

    Like

    1. My Dear Doctor Ritesh,

      Half knowledge is always injourious to health like wise read carefuly PENTAXIM is banned in USA …. way back then why you are promoting such vaccines whoch is banned for USA babies do you beleive it will work for INDIAN babies…
      refresh yourself before you speak otherwise shout your mouth when you never knew in and out about it….
      be loyal to Indian babies not MNC companies if you mind it please dont truth is always bitter…
      PENTAXIM is having only two component of Pertussis where as Indian manufactureres having in there preparation 3000 pertussis component wth bit pain and fever …. whoch is also babies getting after PENTAXIM a Rs. 2500 vaccines So cant you be faith ful to your nation citizen where vaccines is available in only Rs. 585…..
      Please clear your basics the do practice … Your GOD for my home country… mind it.

      mail me if you have some confusion azad.parindea@gmail.com Named Azad…
      shame on yourself a bit

      Like

      1. For all those who call doctors cheats, robber, for charging them bare minimum. (Yes I mean it, it’s BARE MINIMUM….) Here are the facts.

        Average stitching cost by a tailor- 400 & above
        Plumber & electrician cost- 500 & above.
        ( Education— ????? )

        “”Figures compiled by The Lancet show that the cost of a caesarean section is estimated at
        $15,500 in the US, which was only $5,000 costlier than in Australia.

        A normal birth in Australia cost $6,775, while in America it was $10,232.”” Convert in INR.

        People come to us, with expectations of world class treatment, but they don’t want to spend on their own health. They cut around corners & land up in trouble. ( For which they hold doctors responsible. Hypocrites!!!! )

        They self medicate, decide fr themselves which investigations they ll get done, take ayurvedic, allopathic, homeopathic, some baba therapy & wat not. But ll nt take any treatment properly. These days with Google they think they know better than sm1 who has studied medicine fr 10 years. SERIOUSLY?????

        IF YOU CAN’T SPEND ON YOUR OWN HEALTH, YOU ARE LIVING A FOOL’s LIFE.

        Its high time YOU SHOULD TAKE RESPONSIBILITY of your casual attitude towards YOUR OWN HEALTH !!!!!!!!

        Like

    2. Not sure about authenticity of the site but got below info :
      Clearly says go for wP not aP unless necessary

      Primary immunization: The primary infant series should be completed with 3 doses of whole-cell pertussis (wP) vaccines. Vaccination must start at 6 weeks. Acellular pertussis (aP) vaccines should be avoided for the primary series of infant vaccination until or unless there is a genuine compelling reason to use aP vaccine in a given child.

      The recommendation on the use of wP vaccine in primary immunization series is based on the experience with wP vaccines in India and on demonstration of faster waning with aP vaccines in comparison to wP vaccines, and superior priming with wP vaccines than aP vaccines in studies conducted in the industrialized countries after recent resurgence of pertussis in many of these countries using aP vaccines. The evidences and reasons behind above recommendations are discussed in detail in IAP Position Paper on Pertussis immunization [3].

      The aP vaccine combinations should be avoided for the primary series. However, the aP vaccines may be preferred to wP vaccines in those children with history of severe adverse effects after previous dose/s of wP vaccines or children with neurologic disorders, if resources permit. The parents should be counseled about the probable efficacy related disadvantages of using aP vaccines for the primary series. The schedule is same as with wP (DTwP) vaccines. Like DTwP vaccines, DTaP vaccines must not be used in children 7 years or older because of increased reactogenicity.

      link : http://www.indianpediatrics.net/dec2013/dec-1095-1108.htm

      Like

  5. I am not a supporter of Pentaxim. Today only I went for vaccinating my Son and then I came across this posting. This is really disturbing 😦

    Following are the links which provides official reports for Pentaxim Vaccine to be effective in India:
    http://medind.nic.in/ibv/t12/i10/ibvt12i10p793.pdf
    http://clinicaltrials.gov/show/NCT00259337

    I am still not able to find any official link to prove Pentaxim is banned in India ! Requesting to please provide any official link to confirm this is really Banned !!! Thanks for your support.

    Like

  6. Thanks for the post! We administered our child painful DTP (Quadrovax), and then I started hearing rumours of painless (and feverless DTP) – which is Pentaxim. My child has just completed 3 months, and has to take another last shot of DTP soon. It seems, big , money-laundering hospitals ( like Sakra hospital) still prescribe painless DPT. Just wondering… but,thank you so much for your post.

    Like

    1. thanks Binita… though multiple vaccines combined into one is a great option, the disease fighting skills that pentaxim (or any such vaccine with painless pertussis component) offers at later years is under question… hence its better to get it clarified with our paed and opt for safer vaccination methods…

      Like

    2. binita
      let me know when a needle a injection is injected it can be painless ,,,
      this all bullshit huge controvarsy is behind it
      indian mostly doctors except few are behind making money because they alll did their MD MBBS or else by paying bribe So mostly are collecting money …. in other words they are money making machine now….
      try nextime when you able to talk any doctor or physician…
      thanks

      Like

      1. you are 100% correct.Many Doctors are money minded devil.we have to pay what ever this devils ask.There should be correct proportion of doctors for this huge population country.shortage of doctors here think them like a god

        Like

  7. I have given my kid PENTAVAC PFS (which consists of DTP, HepatitisB, Haemophilus Type b, conjugate vaccine)

    its almost like pentaxim, but painfull dose though.

    by reading your info i realised, a little pain can prevent future causes is good. Come on be a mom. All we need to give a little time for pain that’s it.

    thanks sir.

    Like

    1. Bhargavi open your eyes your enough educated that you can c goood or bad…

      so read at your own then take decision….

      instead of Pentavac if you had given Easyfive would be good choice

      but u didnt becuz its your child specialist mistake because he want to earn more money no matter to him … coz hes earning more ….

      Like

      1. Mr Azad , I am seeng here you post what I feel finally don’t miss guide and don’t promote easy5 …Pentavac ,Shan5 & Acellular is always better as no acellular still banned if it is banned then why IAP recommend ..?

        Like

  8. Just for the record – want to point out that the problem is not with pentaxim. It’s just a brand. The problem is with acellular (painless) pertussis vaccines in general. Pertussis is a serious disease and just to prevent 1-2 days of crying and fever I am not going to compromise on my baby’s immunity. All of us moms have taken feb painful whole cell vaccine in childhood. It’s not a big deal when you consider how bad pertussis is. Just take the painful in end give Crocin drops instead if running after pentaxim. It will be over in 2 days. Just my two cents.

    Like

    1. i have just tried to say what this vaccine is capable of and what not…my point is around the presence of acellular component for pertussis as well and whatever info i gathered from my paed…

      Like

  9. I want to tell my story…and now I am confused….

    Very first I have given my kid first dose of DTP ( regular vaccine…painfull & less costly..)…after giving the vaccine ..my kid got huge fever & went to convulsion…got gull body stiffed & eyes started rolling inside…We immediately admitted him hospital…there we found he cannot handle the fever usually because of DTP vaccine….we kept him in hospital for 2 days …doctor suggested for next DTP vaccines go for DTaP ( Pentaxim …painless…which is costly ..)….

    Hence we get done next 2 DTap Doses & first DTaP booster at 18 months….

    Now he completed 5 years & need to provide ….second Booster of DTaP…..My confusion is
    …as I cannot go for regular DTP vaccine…& DTaP Banned by the governments…

    What is answer to this problem….what should I do ?

    Like

  10. my baby boy had given a shot PENTAXIM 8 days ago.. i am worried because yesterday i notice that my baby crossing his eyes many times. if i did’nt run my hand to his face he might not stop crossing his eyes. it started when his doctor injected him that PENTAXIM VACCINE and after a week this happen. for now, i can’t contact his pedia probably by tommorrow. mm im worried because of what i red about the pentaxim victim. please give me some advise on what to do to my child.

    Like

      1. everytime u vaccinate ur child… ask for the vaccination label to be sticked in ur baby’s medical file… this helps to find out abt the details of the vaccine – like batch, expiry, etc.

        Like

    1. Vacinnes injure children like this all the time, and it never gets reported by the doctors. Demand that your doctor report this incident. Your doctor will attempt to tell you it’s “normal’. But consider this – if your child’s eyes are crossing immediately after a vacinne, think of the neurological damage that has been done. The brain controls the eyes.

      Parents, vacinnes are not what you think – stop damaging your children. Check out drtenpenny.com.

      Like

  11. Hardly found any reference to infanrix on this page. My doc has suggested infanrix as an option for my 18 month old- any of you have had that given?

    Like

      1. Even my son had gt 2 injctions fr ds a pentaxim is unavailable, he s 2 minth in age and cryng badly.. I hv already given crocin twice in a gap of 4 hours, i wana knw How long does the pain last and by when will it reduce

        Like

  12. Even my daughter had her dtp vaccine scheduled on 19th March, we waited for 2 weeks for Pentaxim and finally gave her Easy 5 last week. Baby shrieked in pain at the time of the shot and continued to be in pain and fever for full 24 hrs.. had to give her paracetamol every 4 hrs..
    In Mumbai, each hospital chain has an affinity for a particular vaccine brand. therefore in absence of Pentaxim,, easy 5 was the only option given.
    My friend is a scientist in sanofi, the company making Pentaxim.. The reason its out of market however is not because its banned by the govt. They are coming up with a new version which will be working on 7 diseases. He however agreed the slightly less effectiveness of the pertusis strain, but he said its too small for the population to be worried about an outbreak of the disease..
    I guess even GSK too have a painless, feverless vaccine called infarnix??
    more than 65% of the world babies are vaccinated with DTaP ( painless, fever less) vaccine, so i dont think its such a big issue though…seeing our LO shriek in pain is a big big issue im sure

    Like

    1. okay.. general word everywhere on the internet and even amidst doctors about pentaxim is that it is not completely effective against pertussis in the long run…

      yeah.. its so tuf to see our LO wail in pain 😦

      Like

  13. hello, me and many other mothers have already given our babies 1, 2 or 3 doses of pentaxim ,what can we do now? do we have to give again for pertussis ?

    Like

  14. of course DTP vaccines are born to pain, though Qudravac is the best option to avoid chances of infection in later stages of child’s life!
    as every one knows: NO PAIN NO GAIN

    Like

  15. I had a similar experience and my child was given quadravac too. Its been 2 weeks and the swelling subsided… but there seems to be a small lump (apparently painless and not very prominent as I can notice it only when i feel the area). Did you have something similar? will it go away with time?

    Like

  16. Thanks for your post,
    my baby is due for second shot in two days and I was unable to get hold of PENTAXIM. even getting it for first dose was also a good search. I will speak to my paediatrician but still thought of having baby in pain is still frightening.

    Like

    1. yeah.. it has been on low stock since January this year & this news of a ban altogether suddenly… there is another vaccine EASYFIVE…tat too is banned by WHO and already only scarcely available.. 😦

      the baby cries crazily outta pain for sure… with paracetamol drops to the rescue u can manage…

      Like

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